Membrane and liquid allografts, derived from the amnion.

The human amniotic placental membrane has become a novel source of regenerative medicine, due to the amnion’s natural role of facilitating the generation and growth of complex tissues. Axolotl Biologix provides two classes of amnion-derived products: injectable fluid allografts (Axolotl Ambient™ and Axolotl Shot™) and dehydrated human amnion membrane (dhAM) allografts (Axolotl Graft™ and Axolotl DualGraft™). Both product lines are derived from the amniotic components of the placenta and support soft tissue repair and reconstruction. Axolotl products are only intended for use in the domestic United States.

Not all amnion products are created equal.

Much of the amniotic fluid in the market today is aspirated amniotic fluid. This means that the fluid is extracted from the womb as part of a C-section delivery. This fluid may contain debris as well as metabolic waste byproducts and is subject to donor variability. Axolotl fluid is different. Our Axolotl BioSym™ process allows us to isolate the cells in the amniotic membrane and culture them in a regulated tissue culture environment, reducing donor-to-donor differences. Under our conditions, these cells can reliably generate new, clean, “unused” fluid that is rich in growth factors and cytokines—the Axotome™.

Not all amnion products are created equal.

Our process, from start to finish.

Our Products

Please reach out to a member of our clinical team to help you determine the type of product that best suits your practice.

Amnion-derived regenerative fluid.

Axolotl Biologix produces regenerative fluid allografts (Axolotl Ambient™ and Axolotl Shot™) that contain a rich combination of cytokines, amino acids, carbohydrates, hyaluronic acid, extracellular matrix proteins, and growth factors. These secreted proteins—the Axotome™—are well characterized in the scientific literature as essential for fetal growth and development. They have also been described to promote endogenous regeneration and repair of damaged tissue.

Axolotl Ambient™ is maintained at ambient temperature (25±7°C, 77±13°F) for simple and easy storage and use.
Axolotl Shot™ is a pre-loaded syringe of Axolotl Ambient™.

Amnion-derived regenerative fluid.

Axolotl Ambient™ is maintained at ambient temperature (25±7°C, 77±13°F) for simple and easy storage and use.
Axolotl Shot™ is a pre-loaded syringe of Axolotl Ambient™.

Scaffolding that supports the native regenerative process.

The amniotic components used in Axolotl Graft™ and Axolotl DualGraft™ (single and dual layer allografts) create a natural 3-D extracellular matrix scaffold for cellular attachment. Axolotl Graft™ and Axolotl DualGraft™ help establish an environment to promote the patient’s native cell migration and proliferation. Amniotic tissues are reported to contain cytokines and growth factors which can stimulate the native synthesis of key extracellular matrix proteins such as collagen and the chemotaxis of native cells to support repair and regeneration of soft tissues.

Which product is right for your patients?

It’s all in the science.

Axolotl Biologix is focused on developing novel products that are safe and effective. We are dedicated to providing a level of quality and service to our clients that is a cut above the field. Axolotl is actively developing future products that will continue to foster regeneration and healing. Interested in learning more about the science behind Axolotl products? Check out our Science & Research section for Peer-Reviewed Papers, White Papers and Posters.